Hypothyroidism or thyroid failure is a clinical syndrome of the endocrine system that arises from a deficiency of thyroid hormones (thyroxine or triiodothyronine and tetraiodothyronine) produced by the thyroid gland and resulting in a general reduction of all the body’s metabolic processes. This endocrine disorder can cause a range of symptoms such as fatigue, poor cold tolerance and weight gain. In children, hypothyroidism leads to delays in growth and intellectual development. The diagnosis of hypothyroidism, when suspected, can be confirmed by blood tests that measure the levels of thyroid stimulating hormone and the thyroxine. There is a medication for hypothyroidism.
Hypothyroidism can be well treated with levothyroxine, whose dosage is adjusted according to the symptoms and normalization of the levels of thyroxine and TSH. In Western countries, hypothyroidism occurs in 0.3% -0.4% of individuals. The tablet ahould be usually taken every day, before breakfast, at a dose determined by the physician. Few drugs interfere with the simultaneous intake of levothyroxine, reducing absorption; among them we recall only antacids, and supplements containing calcium. It is important that the patient takes regular replacement therapy with levothyroxine. If you forget to take it in the morning, it can be taken even later in the day; if you are certain to have missed the entire daily intake, you can split a missed daily dose, in the following days. Dogs are also known to develop hypothyroidism and in rare circumstances even cats and horses.
People with hypothyroidism often appear to be asymptomatic or have only mild symptoms. Numerous signs and symptoms are associated with hypothyroidism and may be related to the underlying cause or the effects of thyroid hormone deficiency. Hashimoto’s thyroiditis can occur with the presence of struma (goiter) due to an enlarged thyroid. The appetite of the patient is compromised, it can cause fatigue, decreased heart rate, sometimes weight gain, constipation, mental dullness, excessive daytime sleepiness (the patient can get to sleep 10-14 hours a day) , muscle numbness that sees the muscles be released slowly after contraction, decreased metabolism of all the endocrine glands with the related disorders arising therefrom.. Sometimes it can be found reactive hypoglycemia (a drop in blood sugar after a meal rich in carbohydrates, with symptoms such as drowsiness and anxiety).
The addition of liothyronine (synthetic T3) to levothyroxine is a strategy suggested as a measure to better control the symptoms, but still this has not been confirmed by studies in this regard. In 2007, the British Thyroid Association has stated that the combined therapy with T4 and T3 has led to a higher rate of side effects and no benefit compared to T4 from solo.Allo same way, the US guidelines discourage the combination therapy, just for lack of evidence, even though they recognize that some cases have benefited from this approach. The treatment with the only liothyronine is not supported by enough studies in this regard and also, because of its short half-life, should be taken more frequently.
In conclusion, hypothyroidism can cause many symptoms and can not be left untreated. A medication for hypothyroidism you can use is levothyroxine. It helps treat hypothyroidism, but you have to make sure to always use the right amount because it can cause side effects. You have to take the medication daily and make sure not to take it with antacids and calcium supplements.